I am a PhD student working on novel stimuli-responsive nanomaterials as antimicrobials. I graduated from the University of Santiago de Compostela (Spain) in Pharmaceutical Sciences in 2012 with a Minor Thesis. During this time I developed, under the supervision of Prof Christian F. Masaguer, the synthesis and biological evaluation of new family of dopamine receptor ligands. I then moved to the private sector, and carried out an MSc in the pharmaceutical company InKemia-IUCT (Spain) with a research project about the high-throughput biosynthesis of nucleoside analogs and their biological evaluation as anti-breast cancer drugs. On my spare time, I like to play rugby and have a passion for music. I have played the bass for two bands.
- Research Career:
- USC, Spain. Research student on Drug Discovery in the group of Prof. Enrique Raviña, 2010 – 2011.
- USC, Spain. Undergraduate Research Scholarship in the group of Prof Christian F. Masaguer, 2011 – 2012.
- USC, Spain. Minor Thesis “Synthesis of novel 1,4-disubstituted triazoles as potential D3 receptor ligands by means of Click Chemistry” in the group of Prof Christian F. Masaguer, 2012 – 2013.
- University of Birmingham, UK. PhD student in the School of Chemistry. 2013 – Present
Publications in Peer Reviewed Journals
- Insua, I. et al. Synthesis and binding affinity of new 1,4-disubstituted triazoles as potential dopamine D3 receptor ligands. Bioorg. Med. Chem. Lett. 2013, 23, 5586–5591.
- Monzó, J., Insua, I., Fernandez-Trillo, F., and Rodriguez, P. Fundamentals, achievements and challenges in the electrochemical sensing of pathogens. Analyst, 140, 7116–7128 (2015).
- I. Insua et al., Enzyme-responsive polyion complex (PIC) nanoparticles for the targeted delivery of antimicrobial polymers. Polym. Chem. 7, 2684–2690 (2016).
- Insua, I., Wilkinson, A., and Fernandez-Trillo, F. Polyion complex (PIC) particles: Preparation and biomedical applications. Eur. Polym. J. (2016), 81, 198–215.
- I. Insua, S. Majok, A. F. A. Peacock, A. M. Krachler, F. Fernandez-Trillo, Preparation and antimicrobial evaluation of polyion complex (PIC) nanoparticles loaded with polymyxin B, Eur. Polym. J. (2016), 10.1016–j.eurpolymj.2016.08.023.
- Insua, I., Zizmare, L., Peacock, A. F. A. F., Krachler, A. M. & Fernandez-Trillo, F. Polymyxin B containing polyion complex (PIC) nanoparticles: Improving the antimicrobial activity by tailoring the degree of polymerisation of the inert component. Sci Rep 7, 9396 (2017).
Poster Contribution to Conferences